According to U.S. BIOCOMPARE Technology News reports, UCLA, David Wong, MD, and colleagues found, testing the saliva of four cancer-related mRNA can be used to identify health and oral squamous cell cancer, the efficiency of up to 91%. This is the first time found that the mRNA content of saliva can be used to monitor cancer development. The researchers believe that, with the other relevant mRNA detection improved in this way will be able to achieve 99% to 100% in order to identify the accuracy of oral squamous cell carcinoma.
Wong and his colleagues previously analyzed human saliva, usually containing approximately 3,000 different mRNA, of which 280 kinds are often found in the saliva of healthy. Researchers as a benchmark collection of 32 recently diagnosed with oral squamous dental equipment cell carcinoma, and not the treatment of patients with saliva, an analysis of the different mRNA levels in the form.
It was found that the saliva of cancer patients, 1,679 gene expression and health. Further analysis revealed that seven mRNA content increased 3.5 times. The researchers then studied for four in which the content while increasing mRNA. These four mRNA are IL1B, OAZ1, SAT, and IL-8 and other gene products.
Researchers in the case of saliva samples from unknown Failed fillings cause cancer sources, the use of this way can be achieved in 90% of cancer samples to identify the rate and the sensitivity and specificity through blood tests show should be used to detect this cancer.
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